CELL RENEW ACTIVE SOLUTION is a single-dose, highly concentrated ampoule developed within Korea’s advanced K-Derma and functional cosmetics ecosystem. Manufactured in a Korean FDA–registered, GMP-certified facility, the product is positioned as a bio-active cellular support solution designed to promote tissue balance, inflammation modulation, circulation support, and regenerative skin and tissue health.

The formulation centers on Minexin™ Bio-Mineral Water, a patented ingredient system combined with botanical extracts, probiotics, trace minerals, and bio-active compounds. The product is marketed as a cosmetic / functional topical ampoule in Korea but is frequently referenced in integrative, alternative, and regenerative wellness settings due to its biological signaling profile.

Core Research Rationale

Inflammatory Signaling Modulation

Internal research materials associated with the formulation indicate activity related to inflammatory gene expression regulation, including pathways associated with Transforming Growth Factor Beta-1 (TGF-β1).

TGF-β1 is extensively documented in public scientific literature as a master regulator involved in:

• Immune response modulation
• Wound repair and extracellular matrix remodeling
• Angiogenesis and microvascular development
• Cellular differentiation and apoptosis
• Inflammation resolution signaling

The formulation is proposed to support endogenous signaling environments rather than act as a direct agonist or inhibitor.

Composition Overview (Research-Relevant Categories)

1. Minexin™ Bio-Mineral Water System

A proprietary mineral-structured aqueous system containing trace and macro elements including (but not limited to):

• Magnesium (Mg)
• Calcium (Ca)
• Silicon (Si)
• Boron (B)
• Manganese (Mn)
• Strontium (Sr)
• Lithium (Li)
• Vanadium (V)

Research relevance:

• Cellular ion homeostasis
• Enzyme cofactor activity
• Antioxidative defense mechanisms
• Vascular and connective tissue integrity

2. Botanical Bio-Active Extracts

Reported botanical components include extracts traditionally associated with:

• Anti-inflammatory activity
• Antimicrobial properties
• Microcirculatory support
• Tissue-soothing effects

Representative extracts:

• Ginseng
• Peony
• Myrrh
• Lonicera japonica
• Cnidium monnieri
• Rhus semialata
• Xanthium strumarium

Research relevance:

• Cytokine expression studies
• Oxidative stress response
• Tissue inflammation models

3. Probiotic-Derived Components

Probiotic-associated bio-actives derived from:

• Streptococcus thermophilus
• Lactococcus lactis

Research relevance:

• Immune signaling modulation
• Inflammatory pathway regulation
• Microbiome-host interaction modeling (non-viable derivatives)

Proposed Research Applications

Laboratories may consider CELLRENEW ACTIVE SOLUTION for investigation in the following non-exhaustive research domains:

1. Cellular & Molecular Biology

• Inflammatory gene expression profiling
• TGF-β–associated pathway modulation
• Oxidative stress response assays
• Fibroblast, keratinocyte, endothelial cell models

2. Tissue & Regenerative Research

• Wound-healing models
• Extracellular matrix remodeling
• Angiogenesis assays
• Connective tissue integrity studies

3. Neuro-Inflammatory & Pain Research (Exploratory)

• Peripheral nerve inflammation models
• Neuroimmune signaling pathways
• Post-inflammatory recovery environments

4. Translational & Integrative Research

• Multi-component bio-active system modeling
• Synergistic mineral–botanical interactions
• Delivery and “homing” efficiency of co-administered actives

Administration & Handling (Research Context)

• Supplied as single-dose sterile ampoules
• Intended for controlled laboratory handling
• Suitable for:
  • In vitro dilution studies
  • Ex vivo tissue exposure
  • Controlled exploratory delivery models

Storage & handling protocols should be established by the receiving laboratory in accordance with internal research standards.

Manufacturing & Quality Context

Highly Concentrated Bio-Active Polypeptide & Mineral Ampoule
Made in Korea | GMP (ISO 22716) Certified Facility

Ensures batch consistency, traceability, and process reproducibility, which are relevant for research repeatability.

Research Status & Limitations

• The formulation has observational and internal research support
• No FDA drug approval or therapeutic claims are implied
• No clinical efficacy claims are established
• Intended strictly for research and investigational purposes

Disclaimer

This material is provided for research and informational purposes only.
It is not intended to diagnose, treat, cure, or prevent any disease and should not be represented as a pharmaceutical or medical therapy.

All experimental use should be conducted under appropriate institutional review, ethical oversight, and regulatory compliance.