Epithalon (also known as Epitalon or Epithalamin) is a synthetic tetrapeptide derived from the naturally occurring pineal gland peptide Epithalamin.

It is widely studied for its ability to stimulate telomerase activity, restore circadian rhythm, and promote healthy aging by regulating endocrine and immune balance.

Epithalon supports cellular longevity, DNA repair, and antioxidant protection, making it one of the foundational peptides in anti-aging and longevity research.

RESEARCH

Epithalon (Epitalon) is a synthetic tetrapeptide derived from the naturally occurring peptide Epithalamin. It has been extensively studied for its role in promoting cellular health and longevity by influencing the activity of telomerase, a key enzyme involved in DNA repair and cellular aging. Epithalon is provided in lyophilized powder form for research applications focused on aging, cellular repair, and regeneration.

Chemical Information:

• Molecular Formula: C14H22N4O9
• Molecular Weight: 390.35 g/mol
• Sequence: Ala-Glu-Asp-Gly

Description:

Epithalon (Epitalon) is a synthetic tetrapeptide provided exclusively for qualified laboratory research. This compound is intended solely for in vitro experimental studies under controlled conditions. The material is supplied in lyophilized powder form for structural and biochemical analysis in non-clinical research settings. No claims regarding biological activity, therapeutic effects, or clinical applications are made or implied research purposes. No claims regarding biological activity or effects are made or implied. Epithalon is provided in lyophilized powder form for research applications focused on aging, cellular repair, and regeneration.

Research Applications:

• Support Cellular Longevity: Investigate its ability to activate telomerase, promoting DNA repair and extending cellular lifespan.
• Promote Healthy Aging: Explore its effects on oxidative stress reduction and cellular rejuvenation.
• Enhance Immune Function: Study its potential to regulate the immune system and improve overall resilience.
• Improve Sleep Regulation: Examine its role in regulating circadian rhythms and improving sleep quality.

Storage and Handling:

• Store lyophilized powder at -20°C.
• Once reconstituted, store at 2-8°C and use promptly.
• Maintain aseptic techniques during handling to ensure sterility.

Product Specifications:

• Purity: ≥99% (HPLC Certified)
• Appearance: Lyophilized white powder
• Solubility: Soluble in bacteriostatic water

Compliance Notice:

Epithalon is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

Key Benefits:

• Activates telomerase enzyme, helping protect and extend telomere length in aging cells
• Restores circadian rhythm by normalizing melatonin and cortisol cycles
• Supports mitochondrial energy production and DNA integrity
• Enhances immune function and reduces oxidative stress
• Improves sleep, cognitive performance, and emotional balance
• Promotes skin regeneration and youthful vitality through improved cell signaling

Mechanism of Action (Simplified):

• Stimulates telomerase enzyme activity → delays cellular senescence and promotes chromosomal stability
• Regulates pineal and hypothalamic signaling → restores neuroendocrine rhythm
• Enhances antioxidant defenses (↑ superoxide dismutase, ↓ lipid peroxidation)
• Modulates expression of aging-related genes and promotes homeostatic cellular function
• Supports melatonin synthesis and synchronizes circadian rhythms for improved systemic recovery

Applications / Possible Uses:

• Longevity and anti-aging research
• Sleep and circadian rhythm regulation
• Cellular rejuvenation and oxidative stress reduction
• Cognitive and neuroendocrine health protocols
• Often combined with Thymalin and TA1 for systemic immune and longevity optimization

Form / Notes:

• Lyophilized vial for reconstitution
• Ideal for standard longevity and circadian studies