GLP-1 S is a long-acting analogue of the naturally occurring glucagon-like peptide-1 (GLP-1).

It enhances glucose-dependent insulin secretion, slows gastric emptying, and suppresses appetite, making it a leading compound for body-weight reduction and metabolic balance.
Beyond weight loss, it improves glycemic control, lipid metabolism, and cardiovascular markers, making it a cornerstone peptide in metabolic-optimization research.

RESEARCH

GLP-1 S is a synthetic peptide analog formulated for in vitro research involving analog stability and structural modeling. It has been studied in non-clinical environments for its potential to resist enzymatic breakdown and support laboratory modeling of receptor interaction mechanisms.

Chemical Information:

• Molecular Formula: C187H291N45O59
• Molecular Weight: ~4113.58 g/mol
• Sequence: HAEGTFTSDVSSYLEGQAAKAibEFIAWLVKGRG-NH2 (Aib = α-aminoisobutyric acid; Lys26 acylated with C18 fatty diacid)

Description:

GLP-1 S is a synthetic peptide analog formulated exclusively for in vitro research involving analog stability and structural modeling. It is intended solely for laboratory studies focused on analog stability and structural modeling. It has been studied in non-clinical environments for its potential for resisting enzymatic breakdown and enhancing receptor interaction modeling in controlled research setting.

Research Applications:

• Structural investigation of peptide analog stability
• Modeling of receptor-ligand binding interactions in assay conditions
• Conjugation strategy comparisons in synthetic research
• Environmental degradation and preservation analysis under lab simulation

Storage and Handling:

• Store lyophilized powder at -20°C
• Once reconstituted, store at 2–8°C and use promptly
• Use aseptic handling protocols to preserve sterility

Product Specifications:

• Purity: ≥99% (HPLC Verified)
• Appearance: Lyophilized white powder
• Solubility: Soluble in bacteriostatic water

Compliance Notice:

GLP-1 S is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. This product has not been evaluated by the FDA and is not to be used for therapeutic, diagnostic, or clinical purposes. Any misuse of this product may violate applicable laws and regulations. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.

Key Benefits:

• Reduces appetite and caloric intake through central satiety signaling
• Improves insulin sensitivity and stabilizes post-meal glucose levels
• Supports gradual and sustained fat loss without muscle depletion
• Improves lipid and cardiovascular profiles (↓ LDL, ↑ HDL)
• Enhances pancreatic beta-cell preservation and glycemic resilience
• Promotes metabolic flexibility and energy efficiency

Mechanism of Action (Simplified):

• Agonizes GLP-1 receptors in the pancreas and brain → increases insulin secretion only when glucose is elevated
• Delays gastric emptying → prolonged satiety and reduced food intake
• Suppresses glucagon release → decreased hepatic glucose output
• Enhances hypothalamic appetite control → reduced cravings and improved meal regulation

Applications / Possible Uses:

• Weight-management and obesity-reduction protocols
• Metabolic-syndrome and insulin-resistance studies
• Appetite-control and satiety research
• Combination therapy with Cagrilintide or 5-Amino-1MQ for enhanced metabolic synergy

Form / Notes:

• Lyophilized peptide for reconstitution
• Standard research doses for appetite and glucose control