Ipamorelin is a selective growth hormone secretagogue (GHS) that mimics the effects of ghrelin, the body’s natural “growth hormone–releasing” peptide. It stimulates the pituitary gland to release endogenous GH without significantly affecting cortisol or prolactin levels, making it one of the cleanest and most controllable GHRPs available.
RESEARCH
Ipamorelin is a selective growth hormone secretagogue peptide known for its ability to stimulate the release of growth hormone (GH) by targeting the ghrelin receptor. Ipamorelin is extensively studied for its role in enhancing anabolic processes, supporting recovery, and promoting energy balance. It is provided in lyophilized powder form for research applications related to growth hormone modulation, tissue repair, and metabolic studies.
Chemical Information:
- Molecular Formula: C38H49N9O5
- Molecular Weight: 711.86 g/mol
- Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Research Applications:
- Stimulate Growth Hormone Release: Investigate its ability to promote natural GH secretion while minimizing unwanted hormonal side effects.
- Enhance Recovery and Repair: Study its impact on cellular regeneration and tissue healing.
- Support Muscle Growth: Examine its role in muscle protein synthesis and anabolic processes.
- Improve Metabolic Efficiency: Explore its effects on fat metabolism and energy regulation.
Storage and Handling:
- Store lyophilized powder at -20°C.
- Once reconstituted, store at 2-8°C and use promptly.
- This product is not guaranteed sterile. Handle according to institutional safety protocols for non-sterile research materials. Proper aseptic techniques must be employed during handling and reconstitution. Users must follow standard laboratory safety procedures and utilize appropriate personal protective equipment.
Product Specifications:
- Purity: ≥99% (HPLC Certified). Certificate of Analysis available upon request. Exact purity specifications may vary between lots within acceptable analytical margins.
- Appearance: Lyophilized white powder
- Solubility: Soluble in bacteriostatic water
Compliance Notice:
Ipamorelin is FOR RESEARCH USE ONLY. It is not intended for human or veterinary use. Not evaluated by the FDA. Misuse of this product is strictly prohibited and may violate federal, state, or local laws. By purchasing this product, buyer represents and warrants that it will be used only for in vitro research purposes.
Key Benefits:
- Stimulates natural GH and IGF-1 secretion to promote lean muscle and recovery
- Accelerates fat metabolism and improves energy utilization
- Enhances tissue repair, joint health, and collagen synthesis
- Improves sleep quality and recovery cycles
- Supports mood and cognitive clarity through improved GH balance
- Well tolerated with minimal hormonal side effects compared to earlier GHRPs
Mechanism of Action (Simplified):
- Binds to ghrelin receptor (GHS-R1a) on pituitary somatotrophs → triggers pulsatile GH release
- Increases GH pulse amplitude without altering natural rhythm
- Minimal ACTH/cortisol stimulation, making it ideal for long-term use
- Works synergistically with GHRH analogs (e.g., CJC-1295) for amplified GH output
Applications / Possible Uses:
- GH and IGF-1 enhancement research
- Anti-aging and metabolic support protocols
- Recovery and tissue repair programs
- Often stacked with CJC-1295 Without DAC for synergistic GH response
Form / Notes:
Lyophilized 10 mg vial for reconstitution (2–5 mL bacteriostatic water typical).
Used in research and compounding for growth hormone and repair modulation.